rhabdomyolysis induced AKI
Heme pigment released from myoglobin or hemoglobin can cause AKI through intravascular volume depletion (seen in rhabdomyolysis), renal vasoconstriction, direct proximal tubular injury, and tubular obstruction. In rhabdomyolysis, myoglobin is released in the circulation from damaged skeletal muscle. Major causes of rhabdomyolysis include ==trauma, drugs and toxins, seizures, meta