NICE-SUGAR trial
- clinical question: in icu patients, does intensive glycemic control reduce mortality compared to conventional control
- primary: 90 day mortality, hypoglycemic events
- bottom line: intensive control (81-108) leads to higher mortality compared to conventional control (<180)
Backlinks
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Diabetes Inpatient Management
diabetes inpatient management
- Discontinue oral hypoglycemics, especially metformin & sulfonylureas
- Basal Bolus insulin regimen is the preferred guideline driven inpatient regimen
- Inpatient BG goal: 140-180 mg/dL pre-prandially, without severe or recurrent hypoglycemia. ebm NICE-SUGAR trial
- If a patient is having hypoglycemia, they have no BG targets, other than resolving the hypoglycemia.
- Total daily dose (TDD) = ba