Virus Sturcture
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Structures





- enveloped not very stable in environment
- naked: durable protein coat, survive in enviroment
RNA


- host cell synthesize protein for +RNA immediately


- top: positive sense
- middle: negative sense. Nucleic acid not translatable. Must be translated by RNA polymerase, flip 3' and 5' and flip base, strand now looks like +RNA
Replication


- -RNA used to make +RNA genome

- +RNA used to make -RNA genome

DNA

Infectivity

- infectivity: whether or not genetic material can be infectious by itself
Segmented

Overview

- papilloma, polyoma, hepadena: circular DNA
- parvo: smallest, single DNA
- pox: largest, only one replicate in cytoplasm

Vaccine


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