Hypersensitivity
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Type 1
- allergies
- non receptor tyrosine kinase
- epinephrine: vasoconstrict, increase CO, dilate bronchioles
- genetic. Multiple sensitivities
- leukotrienes can be produced quickly as early phase or later as late phase
- chymase, tryptase specific for anaphylaxis, not serotonin
Type 2
Type 3
- complex deposits in lots of places, causing systemic diseases
Arthus
- don't circulate
- form in tissue locally and cause disease
- inject first time, no reaction. Third or fourth time, arthus
- first 3 times, antibody formation. 4th time: reaction
- booster vaccine: antigen into someone previously exposed to vaccine
- diabetes repeatedly inject insulin
Type 4
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