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HPV
HPV
Human papillomavirus (HPV) is a common sexually transmitted virus that causes cervical cancer. In immunocompetent women, HPV usually causes a transient infection. Immunosuppressed patients (eg, HIV infection) are unable to clear HPV and are at increased risk for persistent HPV infection that can progress to cervical dysplasia and cancer. Therefore, patients newly diagnosed
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ID
ID
MKSAP
- Central Nervous System Infections
- Prion Diseases of the Central Nervous System
- Skin and Soft Tissue Infections
- Community-Acquired Pneumonia
- Tick-Borne Diseases
- Urinary Tract Infections
- Mycobacterium tuberculosis Infection
- Nontuberculous Mycobacterial Infections
- Fungal Infections
- Sexually Transmitted Infections
- Osteomyelitis MKSAP
- [[Fever of Unknown Ori
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CNS Lymphoma
CNS lymphoma
Primary CNS lymphoma (PCNSL) is a common malignancy in patients with advanced HIV infections, and is strongly related to the Epstein-Barr virus (EBV). It is usually associated with a significant degree of immunosuppression. Most patients with PCNSL have a persistently depressed CD4 count (< 50/μL).
Institution of HAART therapy is associated with an improved prognosis, especially
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HIV and TB
HIV and TB
- related: HIV, ID, immune reconstitution inflammatory syndrome
- IRIS common in TB patients with HIV
- interferon gamma poor indicator of active TB
- might not mount response to have positive interferon gamma
- treat with rifabutin over rifampin
The timing of his presentation is consistent with the immune reconstitution inflammatory syndrome (IRIS) (median 48 days), the return
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Cryptococcus
cryptococcus
- related: ID, HIV, immune reconstitution inflammatory syndrome
- cryptococcus
- Starting HAART can cause IRIS
- Wait 5 weeks before starting HAART
Types:
- neoformans most common
- agathi: more tropical. Has decreased activity to fluconazole
- usually inhaled
Demographics
- BMT: less b/c ppx fluconazole
- alemduzumab: CD 52
- corticosteroids use
- calcin
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Immune Reconstitution Inflammatory Syndrome
immune reconstitution inflammatory syndrome
- related: ID, HIV and TB, HIV
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HIV and Pregnancy
HIV and pregnancy
- related: HIV
The risk of perinatal HIV transmission directly correlates with maternal HIV viral load. Antiretroviral therapy (typically, highly active antiretroviral therapy [HAART]) is continued throughout pregnancy as it is safe, treats maternal disease, and prevents perinatal transmission by suppressing viral replica
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HIV Resistance Testing
HIV resistance testing
- related: HIV
Viral resistance testing should be performed at baseline to ensure selection of a fully active regimen and should be repeated if the viral load increases during antiretroviral treatment. The most common reason for breakthrough viremia is poor medication adherence. In general, plasma levels of HIV RNA must be greater than 500 copies/mL to provide enough virus for resistance testing.
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HIV Testing
HIV testing
- related: HIV
The CDC, American College of Physicians, Infectious Diseases Society of America, and U.S. Preventive Services Task Force (USPSTF) recommend universal screening for HIV in all adults at least once. The USPSTF suggests those at higher risk (injection drug users and their sexual partners, people who exchange sex for money or drugs, sexual partners of HIV-infected persons