Glucocorticoids
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Eicosanoids
- eicosanoids include leukotrienes, PGs, TXs
- block PGE2: improvement in first 4 conditions with price of renal vasoconstriction
COX
Drugs
NSAIDS
- effects similar to steroids but not steroids
- ketorolac: often IM in ER for pain
- traditional NSAIDS
COX2
Steroids
- TNF alpha works by activating NF-KB
- feared complication
