Hemeonc

• Keywords:: Step 3, Medicine

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MKSAP

• management of bone metastasis
• Hematopoietic Stem Cells and Their Disorders
• Multiple Myeloma and Related Disorders
• Erythrocyte Disorders
• Iron Overload Syndromes
• Platelet Disorders
• MKSAP Bleeding Disorders
• MKSAP Transfusion Medicine
• Thrombotic Disorders
• Hematologic Issues in Pregnancy
• Issues in Oncology
• Breast Cancer
• Ovarian Cancer
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disseminated intravascular coagulation

• related: Hemeonc, DIC vs liver disease
• tags: #note

Common Causes

Common Causes

• sepsis: not that common
• most common: malignancy (APL), B cell malignancies
• pregnancy/delivery, amniotic fluid

Pathogenesis

• exposure to TF => thrombosis => clotting
• dysregulation of coagulation system: everything ramped up. More coagulation and fibrinolysis

Stage 1

• PT/PTT: normal/low
• microthrombi, schisctocytes
• A