DAPT

• related: Cardiology
• tags: #note

History

90s:

• CURE trial: DAPT in ACS
  • ASA vs ASA and Plavix
  • Improvement in 24 hours, 30 days, and 1 year mortality
  • 2% ARR in composite (MI, stroke, death) 2000s
• Prasugrel vs Plavix: TIMI 38?
• Ticag vs Plavix: PLATO trial: same reduction + mortality benefit over tigag 2016
• Prasugrel vs tigag: prasugrel barely better and safer
• Prasugrel: 1x/day, generic, no dyspnea