Ammonia
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- excess are broken down
- generic way aa metabolized
- amino group passed to a keto to become glutamate
Glutamine
Alanine
- amino group passed to pyruvate to create alanine
- alanine taken to liver but can't be metabolized
Urea
- high levels of glutamate and acetyl coa in fed state
- activate urea cycle
- urea cycle happen in liver
- if no aa ingested, little aa breakdown
- only used in children
- arginine becomes essential
OTC Deficiency
Citrullinemia
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