32 Hypertension
![](https://photos.thisispiggy.com/file/wikiFiles/hFzcvEa.jpg)
- pressure changes throughout day
![](https://photos.thisispiggy.com/file/wikiFiles/MBhQZ0w.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/vTmMbp9.jpg)
- drink alcohol: resistant htn
![](https://photos.thisispiggy.com/file/wikiFiles/ZN6jIDM.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/HqkEW1Q.jpg)
- HTN screening important because association with number of diseases
Complications
![](https://photos.thisispiggy.com/file/wikiFiles/A1EzIj9.jpg)
- rupture of atherosclerosis leads to MI
![](https://photos.thisispiggy.com/file/wikiFiles/3FHweGC.jpg)
- glassy appearing
- leakage of protein materials out of arterial wall
![](https://photos.thisispiggy.com/file/wikiFiles/dCceF06.jpg)
- much less common
- malignant: BP rises rapidly and a lot in short amt of time
- bp so high, basement membrane replicating
- symptoms can occur (usually asymptomatic)
![](https://photos.thisispiggy.com/file/wikiFiles/YU0IIvy.jpg)
- lower density of arterioles
![](https://photos.thisispiggy.com/file/wikiFiles/KyolG47.jpg)
- increased afterload, increased work of heart
- left: nl voltage. Right: higher
- diastolic HF, S4
- LV concentric hypertrophy:
![](https://photos.thisispiggy.com/file/wikiFiles/21vU5aP.jpg)
- lumen same size, wall much thicker
![](https://photos.thisispiggy.com/file/wikiFiles/NkT8FHG.jpg)
- systolic/diastolic rises
- pulse pressure also rises
- when C compliance falls, delta P, change in pressure goes up
- left: compliant vessel, blood flow in and stretch vessel, pressure does not increase that much
- right: vessel can't stretch, pressure increase much higher
Urgency
![](https://photos.thisispiggy.com/file/wikiFiles/oX2qQsA.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/LK6z9zB.jpg)
- confusion
- afterload so high, no blood to heart
![](https://photos.thisispiggy.com/file/wikiFiles/KQPeegU.jpg)
- microangiopathic hemolytic anemia
![](https://photos.thisispiggy.com/file/wikiFiles/XqmIjRg.jpg)
- rapidly progressive and fatal in 1-2 years
- now definition: severe HTN difficult to control
Secondary HTN
![](https://photos.thisispiggy.com/file/wikiFiles/bMIWcGI.jpg)
- secondary HTN either raise CO or raise TPR
![](https://photos.thisispiggy.com/file/wikiFiles/AY7uFxB.jpg)
- cannot excrete Na normally
![](https://photos.thisispiggy.com/file/wikiFiles/3jU2fIq.jpg)
- sympathetic ramped up from repeated episodes of apnea
![](https://photos.thisispiggy.com/file/wikiFiles/A3U0TVM.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/66jSeOQ.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/irXmm7n.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/SdZPci2.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/7WlxLoz.jpg)
- diltiazem drug of choice to treat HTN caused by these 2 drugs
![](https://photos.thisispiggy.com/file/wikiFiles/DPdPWI4.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/3T7YgFI.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/z0tDirU.jpg)
- no sign of volume overload
![](https://photos.thisispiggy.com/file/wikiFiles/ErdfwBV.jpg)
- low plasma renin, high aldosterone. Important
![](https://photos.thisispiggy.com/file/wikiFiles/2iM1oWj.jpg)
- catecholamines released in episodes
![](https://photos.thisispiggy.com/file/wikiFiles/muN5oZ6.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/gpvfYkL.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/vAzqYuC.jpg)
- normal kidney compensates for volume retention
![](https://photos.thisispiggy.com/file/wikiFiles/e1OfV7O.jpg)
- pressure natriuresis: autoregulation. One kidney releasing more renin/Na causing the other to release less
- increased RAAS/BP: normal kidney can't compensate
![](https://photos.thisispiggy.com/file/wikiFiles/c9AUb7a.jpg)
- in setting of renal artery stenosis, pts depend on Ang II's efferent vasoconstriction to maintain GFR
![](https://photos.thisispiggy.com/file/wikiFiles/HUwTskS.jpg)
- association and can develop renal artery stenosis
- healthy women in 40s develop HTN resistant to therapy and has bruit over renal artery
![](https://photos.thisispiggy.com/file/wikiFiles/CMBjFLF.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/gbXaeD7.jpg)
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