26 Renal Tumors
![](https://photos.thisispiggy.com/file/wikiFiles/4YSe5Qz.jpg)
- 1st 3 kidney cancer, RCC most common
- last 3 bladder cancer, transitional most common
RCC
![](https://photos.thisispiggy.com/file/wikiFiles/TnyDe30.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/BICvsug.jpg)
- cigarette and obesity very important
![](https://photos.thisispiggy.com/file/wikiFiles/YR5Cbcf.jpg)
- few pts have classic triad, most just have hematuria
![](https://photos.thisispiggy.com/file/wikiFiles/zmOfrMZ.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/8qW9T5w.jpg)
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![](https://photos.thisispiggy.com/file/wikiFiles/74oc7sQ.jpg)
![](https://i.imgur.com/zyCW5vr.jpg)
- glycogen/lipids do not stain very well
![](https://i.imgur.com/jqElhGp.jpg)
- N: normal
- circle: yellow mass
- F: fat
![](https://photos.thisispiggy.com/file/wikiFiles/2L0Klvy.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/YpAEAtn.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/MT3Z9Qj.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/8udcojy.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/x06jg8W.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/BpaK3B1.jpg)
- IL 2 part of inflammatory response, like giving flu to someone
![](https://photos.thisispiggy.com/file/wikiFiles/7QLVrAk.jpg)
- Plush cancer crab in kidney machine: interferon alpha treats renal cell carcinoma
Wilm's
![](https://photos.thisispiggy.com/file/wikiFiles/TJ2Rzxh.jpg)
- HTN in children very rare
- average age 3
- tumor in child kidney, think Wilm's
- composed of blastema: primitive kidney tissue
- large unilateral flank mass
![](https://photos.thisispiggy.com/file/wikiFiles/CbAsDsu.jpg)
![](https://i.imgur.com/iU7ywGX.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/ZWZ2oiC.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/mfd9ffd.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/vWjmliL.jpg)
- neonatal hypoglycemia
- large tongue
Angiomyolipoma
![](https://photos.thisispiggy.com/file/wikiFiles/bqJh9m0.jpg)
- angio: blood vessel; myo: smooth muscle; lipoma: fat
- cortical tuber: growth or bulge
- very important: leaf-like patches of skin, pale skin in shape of leaf
![](https://photos.thisispiggy.com/file/wikiFiles/ngjft8c.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/QvHoq9y.jpg)
- Lack of migration
- Neocortical tubers: very hard and white. Glia and neurons jumbled up
- Nodules around ventricles
- Brain tumors SEGA
![](https://photos.thisispiggy.com/file/wikiFiles/FrgukU2.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/Gbv5DWa.jpg)
- top: discolored areas
- SEGA: blocking fluid in ventricles = hydrocephalus. Tube to drain extra fluid
![](https://i.imgur.com/uY9S23I.jpg)
- don't worry about histology.
- Big mass in child
![](https://i.imgur.com/KxDg1oy.jpg)
- Looks like fat in middle of kidney
Transitional Cell Carcinoma
![](https://photos.thisispiggy.com/file/wikiFiles/28z4AI8.jpg)
- flat pathway: high grade flat tumor then invades. Early p53 mutation
- papillary: low grade papillary tumor that progress to high grade and then invade. Not association with p53
![](https://photos.thisispiggy.com/file/wikiFiles/injo8EF.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/gW1wfQk.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/oeQQSmy.jpg)
- smoker with hematuria: think bladder cancer
- phenacetin: analgesic
- any industrial job
![](https://i.imgur.com/bizBioe.jpg)
- Cancer crab belt buckle: cyclophosphamide increases risk of bladder cancer (high grade transitional cell carcinoma)
![](https://photos.thisispiggy.com/file/wikiFiles/acvAyhT.jpg)
- cast: glomerular source of bleeding
![](https://photos.thisispiggy.com/file/wikiFiles/kybTNJZ.jpg)
- platinum used for transitional
Squamous Cell
![](https://photos.thisispiggy.com/file/wikiFiles/O2VusdM.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/pIa7Aa2.jpg)
Adenocarcinoma
![](https://photos.thisispiggy.com/file/wikiFiles/nOeEmck.jpg)
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