18 Hodgkin Lymphoma
- lymphocytes form mass: oma
- painful: reactive lymph nodes in infection
- tissue biopsy of mass/lymph node
Reed-Sternberg
Hodgkin Lymphoma
- autoimmune: immune activation
- Owl sitting in weeds: Hodgkin lymphoma = Reed-Sternberg cells that look like "owl's eyes"
- reed sternberg only a small amt of cell in lymph nodes
- most cells are reactive cells reacting to cytokines from reed sternberg: B symptoms more common
- one of the reactive cells: macrophages, containing 1a hydroxylase
- spread from 1 set of nodes to another, very predictable
- variant of reed sternberg: popcorn cells
- tumor forms fibrosis tissues that surrounds tumor, creating nodules
- mixed cellularity: lots of eosinophils
- more the lymphocytes, better prognosis
- enlargement often in nonhodgkin
- most common regimen
- don't memorize
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