15 Lung Cancer
![](https://photos.thisispiggy.com/file/wikiFiles/SSWikqQ.jpg)
- breast: most common for women
- prostate: most common for men
- lung: second most common for both men/women
Risk
![](https://photos.thisispiggy.com/file/wikiFiles/hTGvN7O.jpg)
- cigarettes contain PAH
- radiation to chest
- radon: naturally occurring substance get to homes through ground
Symptoms and Diagnosis
![](https://photos.thisispiggy.com/file/wikiFiles/INaH2cY.jpg)
- may grow into blood vessels and cause bleeding
![](https://photos.thisispiggy.com/file/wikiFiles/Zyvu0I4.jpg)
- benign if same prior
- see coin lesions, first thing to do is to compare with prior Xray
Benign Lung Nodules
![](https://photos.thisispiggy.com/file/wikiFiles/LheK6FL.jpg)
- granulomas: people previously with TB, sarcoidosis
- hamartomas: lesion made of normal tissues but disorganized
![](https://photos.thisispiggy.com/file/wikiFiles/RWw3Lrf.jpg)
- fungal: can be very mild/asymptomatic
- also prior mycobacteria
Primary Lung Cancer
![](https://photos.thisispiggy.com/file/wikiFiles/aLUJlS8.jpg)
- small cell rare but much worse
Small Cell
![](https://photos.thisispiggy.com/file/wikiFiles/cUycJCa.jpg)
- Kulchitsky cells: sea of undifferentiated small cells
- neuroendocrine: associated paraneoplastic symptoms
- neuroendocrine: NSE, NCAM, CD56, chromogranin, synaptophysin
- occur centrally in lung
![](https://photos.thisispiggy.com/file/wikiFiles/1EdNSCh.jpg)
Non Small Cell
![](https://photos.thisispiggy.com/file/wikiFiles/z2SGziv.jpg)
Squamous
![](https://photos.thisispiggy.com/file/wikiFiles/etxbDjd.jpg)
- near center of chest right when primary bronchi branches
Adenocarcinoma
![](https://photos.thisispiggy.com/file/wikiFiles/oIoI6Ef.jpg)
- tumor in nonsmoker and peripheral: think adeno
Bronchioloalveolar Carcinoma
![](https://photos.thisispiggy.com/file/wikiFiles/KKThqeT.jpg)
Large Cell Carcinoma
![](https://photos.thisispiggy.com/file/wikiFiles/Q7UbHUZ.jpg)
- doesn't fit in other types
- very poor prognosis
Carcinoid
![](https://photos.thisispiggy.com/file/wikiFiles/jKeHSZJ.jpg)
- even though has name, rarely causes carcinoid syndrome, more common with GI tumors met to liver
Complications
![](https://photos.thisispiggy.com/file/wikiFiles/gnFwl8V.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/eie6zYT.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/hu7LIWd.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/FDEuciC.jpg)
- different from SVC, just arm edema, no facial edema
- irritating nerves: shoulder pain radiating
![](https://photos.thisispiggy.com/file/wikiFiles/yR7cWy0.jpg)
![](https://photos.thisispiggy.com/file/wikiFiles/sE5K2Fr.jpg)
Backlinks