12 Exocrine Pancreas

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Pancreatic Fluid

• left side: same as plasma

• slow flow rate: all bicarb reabsorbed
• quick flow rate: not enough time to absorb bicarb

Pancreatic Enzymes

• vasovagal reflex
• signal from duodenum to pancreas via vagus nerve

• lipase: fat

Amylase

• active form secreted

• breaks down into smaller saccharides

• only monosaccharides absorbed
• at brush border: rate limiting step

Lipase

Protein

• auto activation of trypsin starts acute pancreatitis