09 Gm indeterminate

• Originally rickettsia species, now its own
• red barn: Gram negative
• Ram inside barn with lock: Obligate intracellular organism
• Walnuts with poop: Contained in spore like structures in animal feces

• Walnuts with poop: Contained in spore like structures in animal feces
• Dust cloud: Transmitted to humans via aerosol transmission, farm animals are major reservoir

• White, clean sheep: No rash caused
• Q horn; Q-fever
• coughing farmer: Pneumonia
• hitting head: Headache
• sweating/red face: Fever
• Liver spot: May cause hepatitis
• Self limiting

Mycoplasma Pneumoniae

• Outside, no walls: "No cell wall, can't appear on gram stain"
• cholesterol rings on goal net: Cell membrane contains cholesterol, stabilize membrane and more flexible

• military uniform: Common in military recruits living in close quarters
• <30: Commonly occurs in young adults

• RBC on ground bound by IgM snow flakes: IgM cold agglutinins cause agglutination/lysis of red blood cells
• Don't eat on ice: "Eaton's agar"
• patchy sky: X-ray shows reticulonodular or "patchy" infiltrate, appears much worse than patients seem clinically
• referee walking: Walking pneumonia, pt not as sick as X ray shows
• target: Erythema multiforme. Target lesions

• Crows: Macrolide for treatment because no cell wall

Rickettsia species

• Inside stadium: Obligate intracellular organism
• All white ppl: Poor gram staining. Giemsa stain for visualization
• pink tennis balls: Weakly gram negative
• deflated tennis balls: Coccobacillary shape
• Coach shirt: Unable to produce CoA, gets it from eukaryotic cells
• NAD+ bottle: Unable to produce NAD+, important for bacterial growth and reproduction, steal from eukaryotic

• Will and Felix: Weil-Felix agglutination test for Rickettsial infections, cross reaction between rickettsia and proteus vulgaris

• Felix sweating/touching head: Headache and fever in early Rickettsial infection
• Rash may be associated with vasculitis
• broken, bright red net and rackets: Vasculitis and inflammation/destruction
• Tires: Doxycycline for treatment

Prowazekii

• Coach with military hat: Affects military camp recruits and prisoners of war (close contact with poor hygiene
• football shaped like louse: Spread by louse, defecates near bite spread to blood by scratching.
• The outbreak board: Illness is called epidemic typhus (more widespread than endemic)

• football formation: Rash starts at trunk, and spreads outward towards extremities
• players red except helmet, hands, feet: Rash spares hands, head, and feet
• Tackled player: Causes myalgia and arthalgia
• coughing from dirt: Causes pneumonia
• confused guy: Encephalitis, with and confusion. can cause coma if very serious

rickettsii

• Rock with legs, derma center arena: Transmitted by direct bite of Dermacentor ticks (sport center)
• Transmitted by direct bite of Dermacentor ticks

• climber at bottom with no rash: Rash not immediate, incubation period between 2-14 days
• 1st climber: Rash begins at extremities. Wall = source of rash
• Rash spreads centrally from extremities
• Climber on top grabbing head, sweating, sore from climb: Symptoms include headache, fever, myalgias