05 Hypoxia

• saturation of hemoglobin depends on PaO2

PaO2

• in arteriole blood
• measures dissolved

• measures saturation

• saturation of hemoglobin depends on PaO2

Hypoxia

• hypoxemia: low number calculated from equation
• hypoxia can be caused by hypoxemia and other things

HF

• hypoxia or ischemia
• pulmonary edema with CHF: may have reduced O2 content

Anemia

• O2 binding capacity reduced
• not enough Hb around

CO

• functional anemia: taking Hb away from O2

Alveolar Gas

• PAO2: O2 partial pressure in alveoli, lower because O2 exchange
• PaO2: lower because mixing of blood from vessels travel through lungs and do not go through alveoli

• gas exchange

• high altitude: low partial pressure of O2