01 Renal Embryology

• initiate kidney dev
• mesonephros also degenerate, except some persists as vas
• bladder not made from kidney

• CD: only portion of nephron from ureteric bud

• metanephric duct form outgrowth, ureteric bud
• ureteric bud send signal to mesenchyme that sends signal back to ureteric bud
• interaction has to be normal for kidney dev

Pathology

• purple: metanephric tissue

• renal agenesis result

• junction between ureter (7) and pelvis (6)

• usually bilateral failure

• can't rise in abdomen

• key feature: cancer at dome