ebm
- ARRIVE: ASA doesn't work for primary prevention
- REDUCE-it: icosapent ethyl decreases mortality for pts on statin and has DM and ASCVD
Cardiology
- Empagliflozin in Heart Failure with a Preserved Ejection Fraction: empagliflozin reduces CV risk and hospitalization for heart failure patients with EF > 40 % with or without diabetes
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Ebm NICE-SUGAR Trial
NICE-SUGAR trial
- clinical question: in icu patients, does intensive glycemic control reduce mortality compared to conventional control
- primary: 90 day mortality, hypoglycemic events
- bottom line: intensive control (81-108) leads to higher mortality compared to conventional control (<180)
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