ITP

Patients with asymptomatic mild thrombocytopenia (platelets >30,000/µL without bleeding) can generally be observed without treatment.
Corticosteroids are a first-line treatment option for patients with symptoms and/or a platelet count of <30,000/µL; the majority of adults respond within 1-2 weeks.
Intravenous immunoglobulin can be considered in patients who have failed or have contraindications to steroid therapy or require a more rapid increase in platelet counts.
Anti-Rh(D) is an alternate treatment option in rhesus-positive non-splenectomized patients.
Rituximab can be considered for patients who have failed initial treatment. Splenectomy is generally reserved for refractory cases .

Bleeding Disorders
Bleeding disorders
- related: Hemeonc
- ITP
Prolonged aPTT and normal PT (INR) suggest an intrinsic pathway defect. Deficiencies of factor XII, prekallikrein, or high molecular weight kininogen all cause a prolonged aPTT without clinical bleeding. Prolonged aPTT with bleeding can occur in congenital or acquired von Willebrand disease and isolated deficiencies of factors VIII, IX, a
Hemeonc
Hemeonc
- Keywords:: Step 3, Medicine
MKSAP

Bleeding disorders